Tech Spotlight: I.DOT MINI, Small Liquid Handler

Liquid Handler: The I.DOT MINI 

Fast. Accurate. Small

This tech spotlight focuses on the liquid handler: The I.DOT MINI that comes equipped with DropDetection, providing users the ability to detect when users run out of source liquid. DropDetection is a patented feature that detects and counts every droplet released during a single dispensing run. It’s a simple and powerful tool enabling droplet verification and protocol optimization.

This innovative solution, mounted under the source well of the I.DOT MINI features a miniaturized light barrier to detect changes in light intensity as drops pass the photoelectric barrier between the source well and the target plate. After the dispensing run, DropDetection delivers color-coded results (green for a successful deposit and red
for an error) that are conveniently stored in a file for easy access.

This lightweight liquid handler uses a single positive pressure channel to generate droplets as small as 8 nanoliters through a nozzle in the well and can produce up to 100 droplets per second.

I.DOT MINI Liquid handler

Key Features for Easy Use

Large dynamic range: Dispenses 8 nl to 500,000 nl of a single source liquid at a time.

Accuracy: Built-in droplet verification I.DOT MINI‘s droplet detection has the capability to detect when users run out of source liquid and can verify total dispense value.

Eliminate cross-over and contamination: The technology enables droplets to be dispensed into the target plate below the source plate. I.DOT MINI eliminates carryover and cross-contamination.

Low dead volume: Well reservoir design ensures dead volume < 1 µl for H20.

Speed: Dispense 10 nanoliters across a 96-well plate in 10 seconds and across a 384-well plate in 20 seconds for 50nl.

To learn about how I.DOT MINI automates life science workflows and executes them more efficiently, download our brochure.

Author: Julie DiRosa, Product Marketing Manager

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