The latest technology for liquid handling tasks.

Fast. Accurate. Unmatched.

Speed and control while eliminating cross contamination

The I.DOT has a patented drop detection system which uses eight individually controlled positive pressure channels to generate droplets from 8 to 50 nanoliters from a small hole at the bottom of each well. Each channel can generate up to 100 droplets per second giving control and speed to the users all while minimizing cross contamination.



Compound dispensing

Dispenses small molecules in aqueous solutions or dimethyl sulfoxide (DMSO).


Assay development

Dispenses small molecules, nucleic acids, drugs, etc. in a multiplexed manner and in direct dilution steps. Ideal for designing individual experiments.


Genomics and proteomics

Leverages miniaturization, low-volume dispensing and low dead volume to efficiently dispense for NGS prep, PCR, extraction and clean-ups.


Cell dispensing

Reproducibly dispense anything from cells in suspension to organoids, while maintaining high cell viability.

Significant reduction of liquid reagents volumes

I.DOT is a premier solution for noncontact liquid handling tasks. Optimizing your workflow to bring intuitive automation, precision and speed to every lab.


Features Designed for Your Success



The technology enables droplets to be dispensed into the target plate below the source plate. I.DOT eliminates carryover and cross-contamination.


Supports multiple liquid classes

Dispenses multiple liquid classes on-demand including aqueous solutions, PCR buffer, DMSO (up to 100%) and glycerol (up to 50%) – and defines liquid class at the well level.



Dispense 10 nanoliters across a 96 well plate in 10 seconds and across a 384 well plate in 20 seconds.


Low dead volume

Automated liquid handling is key for routine single-cell library preparation as it reduces hands on time and operator bias. The I.DOT further optimizes your workflow enabling assay miniaturization. Well reservoir design ensures dead volume <1 µL to conserve valuable reagents and samples.

Application Notes

Written by scientists for scientists, these papers highlight novel ways to optimize one’s research with the I.DOT Liquid Handler.

Fast, Miniaturized and Automated Library Prep for High-quality Single-cell RNA-seq Data

Sequencing Single-cell Genomes of Uncultivated Bacteria in the Human Oral Microbiome

Miniaturization and Automation of a full-length Single-Cell RNA-seq Workflow

Tumor Spheroid Formation Using the I-DOT


Groundbreaking research made using the I.DOT.

Sustainable solutions to the life science industry

The I.DOT lowers your plastic waste and the risk of carryover seen with hand pipetting. Reduce your lab’s carbon footprint and enjoy huge savings on valuable reagents and samples.


We are happy to answer all you questions. Contact us at info@dispendix.com