Latest technology in noncontact dispensing for fast and reproducible results every time.

i.dot non contact automated liquid dispenser and handler

Fast. Precise. Traceable.

The I.DOT is a liquid handler that anyone can use regardless of automation experience. The instrument transfers volumes as low as 8 nL with unrivaled precision and speed while dramatically reducing your laboratory’s plastics and reagent consumption.

Whether you are dispensing enzymes and beads for NGS or qPCR or adding cells, compounds, and buffers for Assay Development or High-throughput Screening, the I.DOT offers unrivaled precision and ease of use for efficient and reproducible sample preparation.

Features Designed for Your Success

i.dot features

1. Reaction Miniaturization

With precise transfers down to 8 nL, DISPENDIX LiquidHandlers enable reaction miniaturization, allowing researchers to run up to 10x as many samples for the same cost to their lab.

2. Low dead volume

With a 1 μL dead volume, no other product enables researchers to transfer their compounds, reagents, and buffers in a more cost-effective and efficient way.

3. Speed & Flexibility

With the ability to dispense a reagent to 384 wells in seconds rather than minutes, DISPENDIX is changing the way researchers think about the automation of their genomics and drug discovery workflows.

I.DOT: How it works

Choose the right I.DOT for your lab

The I.DOT provides users with flexibility in the types of source consumables and destination labware formats that can be used.


S Plates, standard destination

Source Options:


S.60, S.100, S.200 Well Plates support a wide range of liquid classes.

S.Wells contain 80 uL source VolumeL

Destination Options:


Supports 96 flat plates, 384 and 1536 well plates and custom plate format

I.DOT dispendix liquid handling instrument


S Plates, DW destination

Source Options:


S.60, S.100, S.200 Well Plates support a wide range of liquid classes.

S.Wells contain 80 uL source VolumeL

Destination Options:


Supports skirted 96-well PCR plates, Deep-well plates, SBS standard plates, and custom plate format

I.DOT liquid handler


L Plates, DW destination

Source Options:


New L.100 Well Plates available

L.Wells contain 500 uL Source Volume making them more convenient for higher volume multi-well dispensers. (Use fewer Source wells for the same workflow)

Destination Options:


Supports skirted 96-well PCR plates and Deep-well plate



Compound dispensing

Dispenses small molecules in aqueous solutions or dimethyl sulfoxide (DMSO).


Assay development

Dispenses small molecules, nucleic acids, drugs, etc. in a multiplexed manner and in direct dilution steps. Ideal for designing individual experiments.


Genomics and proteomics

Leverages miniaturization, low-volume dispensing and low dead volume to efficiently dispense for NGS prep, PCR, extraction and clean-ups.


Cell dispensing

Reproducibly dispense anything from cells in suspension to organoids, while maintaining high cell viability.

Significant reduction of liquid reagents volumes

I.DOT is a premier solution for noncontact liquid handling tasks. Optimizing your workflow to bring intuitive automation, precision, and speed to every lab.

I.DOT Automated pipette system-min
i.dot volume verification

Real-time volume verification

The I.DOT is the only liquid handler with droplet detection and has the capability to detect when users run out of source liquid and verifies dispensing volume.

I.DOT’s DropDetection is a patented feature that detects and counts every droplet released during a single dispensing run. With integrated droplet detection, DISPENDIX provides researchers with an unparalleled degree of process safety. Imagine knowing for every transfer, the actual volume transferred with an 8 nL resolution. These barriers identify changes in light intensity to identify droplets as they pass the light barrier. After dispensing, DropDetection produces color-coded and text-file-based results.

Application Notes & White Papers

Written by scientists for scientists, these papers highlight novel ways to optimize one’s research with the I.DOT Liquid Handler.

User-friendly automation of full-length single-cell RNA-sequencing with FLASH-seq

Download Application Note

Automated dispensing of Antibodies with the I.DOT


Groundbreaking research made using the I.DOT.

Sustainable solutions to the life science industry

The I.DOT lowers your plastic waste and the risk of carryover seen with hand pipetting. Reduce your lab’s carbon footprint and enjoy huge savings on valuable reagents and samples.


We are happy to answer all you questions. Contact us at info@dispendix.com