I.DOT Liquid Handler
Low-volume Dispensing for Every Lab
 
• Nanoliters & Microliters
• MeOH - 65% Glycerol
• 0.1 Nanoliter Resolution
• 1 Microliter Dead Volume
• 96 or 384 Sources to Any-well
• Integrated Volume Verification
• Shocking Speed, Precision, & Traceability
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Trusted by Scientists Around the World

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Efficient and Reproducible Liquid Handling

Enhance Your Automation Arsenal

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Practice Sustainability

Use a fraction of the pipette tips required by traditional automation, save the planet, and retain your budget.

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Conserve Reagents

Dispense reagents with a 1 μL dead volume and run more samples for the same reagent cost.

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Generate Trustworthy Results

Dispense 4 nL to 30 μL into any SBS format destination labware with a high degree of precision.

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Trust Your Process

Dispense with insight into the actual volume dispensed every time with integrated volume verification.

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Forget About Training

Software for dispensing a constant volume, dilution, normalization, and pooling should not be complicated.

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Deliver Value to Your Lab

Dispense up to 384 source liquids per run at a speed and precision that will continue to surprise you and your colleagues every day.

Fast. Precise. Traceable.

The I.DOT is a liquid handler that anyone can use regardless of automation experience. The instrument transfers volumes as low as 4 nL with unrivalled precision and speed while dramatically reducing your laboratory’s plastics and reagent consumption.

Whether you are dispensing enzymes and beads for NGS or qPCR or adding cells, compounds, and buffers for Assay Development or High-throughput Screening, the I.DOT offers unrivalled precision and ease of use for efficient and reproducible sample preparation.

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Enabling Miniaturization is Our Passion

Although reaction miniaturization is ubiquitous in large pharmaceutical environments, it can be challenging to understand the risks and considerations associated with generating high-quality data in the context of miniaturizing assays.  

The DISPENDIX team has worked through miniaturization of even the most complex NGS workflows, and can help you to scale volumes as low as 1/10th the manufacturer's recommended SOP without compromising data quality.

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Designed for Automation

The I.DOT Liquid Handler has been designed so that I.DOT Source Plates and destination SBS format labware can be reproducibly loaded into the device for reliable integration into any automated work cell.  

With a SiLA2 compliant API and comprehensive integration manual, third party integrators can seamlessly and efficiently incorporate the I.DOT into any automated solution to maximize efficiency, reproducibility, and process safety.

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I.DOT Family

Choose the Best Fit For Your Application

  • I.DOT S

  • I.DOT L

  • I.DOT HT

DISPENDIX I.DOT S Liquid Handler

Optimized for Flexibility

Full Viscosity Range from Methanol to 65% Glycerol

Up to 96 Source Wells with 1 μL Dead Volume

80 μL Source Well Capacity

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DOWNLOAD SPEC SHEET 
DISPENDIX I.DOT L Liquid Handler

Optimized for Genomics

Viscosity Range from Water to 43% Glycerol

Up to 96 Source Wells with 1 μL Dead Volume

500 μL Source Well Capacity

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Optimized for Drug Discovery

Designed to dispense DMSO & Aqueous Solutions

Up to 384 Source Wells with 5 μL Dead Volume

80 μL Source Well Capacity

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FAQ

Our Most Common Questions

How do I know which steps of my process the I.DOT can automate?

The I.DOT can automate the process of dispensing up to 384 liquids into up to 1536 wells of a destination plate!  Since there is a lot of flexibility in the use of the platform, we often recommend the use of the I.DOT for steps where liquids are dispensed into 8 or more destination wells at volumes from 4 nL to 30 μL per well.

Is the I.DOT automation friendly?

Yes! Our customers integrate the I.DOT in varying degrees of complexity from simple integrations with an arm and a liquid handler to large robotic workcells capable of processing thousands of samples per day.

Can the I.DOT Dispense Glycerol, DMSO, and Aqueous Solutions?

The I.DOT can dispense liquids from 0.55 mPa*s (methanol) to 23.32 mPa*s (65% glycerol).  

How do I know that the I.DOT actually dispensed my liquid?

The I.DOT comes equipped with integrated droplet detection that counts the number of droplets dispensed in any given operation.  With these data, the I.DOT software will report to you the theoretical volume dispensed by taking the product of the average droplet size and number of droplets counted.

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GUIDE

Automated Pipetting

Explore the evolution and impact of automated pipetting technology. By embracing automated pipetting, labs can achieve faster, more reliable, and safer workflows.

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The Impact of Robotic Pipetting on Lab Practices

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Tips to Improve NGS Library Preparation

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Enhance Efficiency and Reproducibility with the I.DOT

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