The Many Applications of the I.DOT

I.DOT automates life science workflows and executes them more efficiently.

The I.DOT is a very versatile liquid handler that can be used in many scientific  workflows, saving time on labor intensive tasks and money on tips and costly reagents.

High-throughput screening
• Create multiple permutations of drug concentrations across the well plate with different drug mixtures in each well.
• Add reagents between 8 nanoliters and 500 microliters per well using I.DOT’s high dynamic range.
• Dispense from any source well into any destination well.

Genomics and proteomics
• Enables you to do sample preparation for single cell proteomics for a deep resolution of the proteome.
• Enhance NGS Library Prep and leverage miniaturization, low-volume dispensing and low dead volume.
• Dispense high-viscosity solutions with ease and reduce time

Assay development
• Miniaturize your cellular assays into a 1536- well plate.
• Dispense up to 96 source liquids using a different volume in each well with I.DOT’s DoE-friendliness.

CRISPR reactions
• Leverage I.DOT’s speed, accuracy and low dead volume to rapidly and cost-efficiently set up CRISPR reactions and other gene-editing protocols.

Indexing/Combinatorial dispensing
• Perform complicated dispensing patterns across 96, 384 and 1536-well plates.

Synthetic biology
• Dispense any volume from any source well to any target well like complex DNA structures to sub-cellular components.

Compounds dispensing
• Use the I.DOT to dispense small molecules
• Dispense combinations of serial compound dilutions

Dispensing beads
• Dispense resin-based or magnetic beads reproducibly across your target plates for extraction or cleanups.

Pooling libraries
• CDNA concentrations and I.DOT software calculates the volume needed to achieve the correct concentration to be dispensed.
• Performs this function for up to 96 libraries in under one minute.

Cell dispensing
• Dispense anything from cells in suspension to organoids while maintaining cell viability.

Genomics and proteomics
• Enables you to do sample preparation for single cell proteomics for a deep resolution of the proteome.
• Enhance NGS Library Prep and leverage miniaturization, low-volume dispensing and low dead volume.
• Dispense high-viscosity solutions with ease and reduce time

To learn more about how the I.DOT works , view our demo video.