Scale-up your NGS library prep workflows with I.DOT L

NGS Library Prep with the I.DOT L, scale up workflows and save on reagents with new and accurate liquid handler.


The I.DOT uses eight individually controlled positive pressure channels to generate droplets from 8 to 50 nanolitres from a small hole at the bottom of each well. Each channel can generate up to 100 droplets per second giving control and speed to the users.

It can handle multiple liquid classes, has very low dead volume, and uses the unique built-in droplet verification technology.

I.DOT minimizes the risks of cross-contamination, reduces time and labour, dispenses accurate reagents volumes, lowers cost on reagents and makes the use of pipette tips unnecessary. Overall it increases the reliability and the reproducibility.

I.DOT technology is evolving: I.DOT L - with a large source liquid capacity

In an effort to meet your needs, to improve the productivity, sustainability, and cost-effectiveness of your genomics workflow, our research and development teams worked arduously to create a new liquid handling solution- I.DOT L.

Increase the total dispensing volume by more than 6 times: I.DOT L allows you to technology extend your source volume from existing 80 µl to 500µl per single source well. Increasing the total dispensing volume from 7680 µl to 48000 µl.

Automate liquid class creation: Creating your custom liquid class has never been easier! With the liquid class creation wizard, simply dispense a predefined protocol and fit your custom liquid class perfect to your dispensed reagents.

Automate workflows: The I.DOT L can be integrated in fully automated workstations via its API. With the extension of the source volume, less source plates are needed to fill more destination plates without human interference.


I.DOT L could be a perfect fit for High throughput NGS (Next Generation Sequencing) library preparation workflow.

With high source liquid volume, process multiple plates with unmatchable speed dispense high volumes like 20 µl across 96-well plate in less than 1 minute.

The I.DOT L could be employed in NGS library preparation workflows from the beginning, with nucleic acid extraction in 96-well plates, to the very end, with library amplification and library pooling.

You can leverage I.DOT L to dispense all the reagents required in following stages of NGS library preparation protocols:

  • Sample preparation- High throughput nucleic acids (DNA/RNA isolation)
  • Enzymatic fragmentation
  • End repair and adapter ligation
  • PCR amplification
  • Indexing
  • Library pooling

Get in touch to learn more. Book a demo today.

Interested in learning more about NGS Automation? Read more articles on our blog.


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