The I.DOT contactless dispensing system and its patented Immediate Drop on Demand technology makes it possible for any laboratory workflow to be miniaturized and optimized, with simultaneous verification of the dispensed liquids – in a quantitative and qualitative manner.
In times of increasing laboratory automation and high-throughput experimentation, the need for liquid handling applications in addition to manual pipetting are steadily increasing. This was particularly evident in the challenges posed to mankind by the COVID19 pandemic. The demand for real-time PCRs in Sars-CoV2 diagnostics increased strongly in a very short time, followed by a higher throughput of sequencing of the virus genome. The hour of automated liquid handlers has arrived. In addition, there is a strong interest in the laboratory world to miniaturize assays to save time and reagent costs. An additional useful aspect besides miniaturization, is the reduction of plastic waste (with up to 80% fewer pipette tips& 10x savings in reagent costs), which can be achieved by using I.DOT technology.
The I.DOT is an intuitive, contactless dispensing platform for the deposition of small quantities of liquid, starting from 8 nanoliters up to several microliters at a speed of 100 drops per second and the simultaneous use of up to 96 different liquids. It has a highly versatile use for all life sciences workflows. Starting with the 10-fold miniaturized distribution of master mixes for reverse transcriptions followed by qPCRs or the dispensing of cell suspensions, furthermore dilution series of aqueous and DMSO-containing solutions in compound screening to dispensing tasks that require high combinatorics, such as the distribution of the primers in next generation sequencing or DNA assembly in synthetic biology.
Another exciting application area of the I.DOT is the miniaturization of the sample preparation for proteomics. Here it helps with the distribution of the digestion enzymes and de-alkylating/reducing reagents of single cells or smallest amounts of proteins.
In addition, it is important for the researchers to have confidence in the workflow, since quite often expensive reagents are often involved in the experiments, such a NGS library prep kits.
With the I.DOT, this assurance is achieved with the patented drop detection function. Individual drops are detected and counted during the dispensing process. This enables conclusions to be drawn about the success of the dispensed protocol as well as on the total volume dispensed.
Immediate Drop-on-demand Technology (I.DOT) is the only instrument in the world to incorporate bubble detection and the capability to detect when users run out of source liquid and verifies dispensing volume.
Learn more about the I.DOT and schedule a demo today.